HuagongsheHuagongshe Chemistry Print Report · For research reference only
ethyl pyrido[3,4-b]pyrazine-6(5H)-carboxylate → ethyl 7,8-dihydropyrido[3,4-b]pyrazine-6(5H)-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | ethyl pyrido[3,4-b]pyrazine-6(5H)-carboxylate | HCID 57420579 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | ethyl 7,8-dihydropyrido[3,4-b]pyrazine-6(5H)-carboxylate | HCID 57420580 | — |
Reaction Steps
To a solution of ethyl pyrido[3,4-b]pyrazine-6(5H)-carboxylate (149 mg, 0.726 mmol) in EtOAc (25 mL) is added 10% Pd/C (100 mg). The mixture is hydrogenated at 30 psi. overnight. The mixture is filtered through Celite and the solvent removed under vacuum to yield the title compound. MS (+VE) m/z 208.16 (M++1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07795262B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-10fcb71509cb4251818601b38389e3ee |
| Source note | uspto-grants-2010_09 |