Cyclopentanone → N'-cyclopentylidene(tert-butoxy)carbohydrazide

HRID 1713165Notes

Reaction equation

HRID 1713165 reaction equation
[C:1]1(=O)[CH2:5][CH2:4][CH2:3][CH2:2]1.[NH:7]([C:9]([O:11][C:12]([CH3:15])([CH3:14])[CH3:13])=[O:10])[NH2:8]>CO>[C:1]1(=[N:8][NH:7][C:9]([O:11][C:12]([CH3:15])([CH3:14])[CH3:13])=[O:10])[CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

4

Reactant 2

HCID 8452CyclopentanoneHCID 70091tert-Butyl carbazate

Product 1

HCID 4058837N'-cyclopentylidene(tert-butoxy)carbohydrazide

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A mixture of cyclopentanone (4.0 g, 47.5 mmol) and tert-butyl hydrazinecarboxylate (6.28 g, 47.5 mmol) in MeOH (100 mL) is stirred at rt for 2 hr. The solvent is removed in vacuo to yield the title compound as a white solid, which is used in the next step without further purification. MS (M+1): 199.1.

Workup

  1. customThe solvent is removed in vacuo

Sources & evidence

ORD record
ord-874342629b0241b4b4ea806f89803c64
Source dataset
uspto-grants-2010_09
Patent number
US07795262B2

Reaction notes

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