Hydrochloric Acid → 2-cyclopentyl-2,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine hydrochloride

HRID 1713167Notes

Reaction equation

HRID 1713167 reaction equation
[CH:1]1([N:6]2[CH:21]=[C:9]3[CH2:10][N:11](C(OC(C)(C)C)=O)[CH2:12][CH2:13][C:8]3=[N:7]2)[CH2:5][CH2:4][CH2:3][CH2:2]1.[ClH:22]>O1CCOCC1>[ClH:22].[CH:1]1([N:6]2[CH:21]=[C:9]3[CH2:10][NH:11][CH2:12][CH2:13][C:8]3=[N:7]2)[CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 57356886tert-butyl 2-cyclopentyl-2,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate

Product 1

HCID 574499462-cyclopentyl-2,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine hydrochloride

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent2×

Procedure

To a solution of tert-butyl 2-cyclopentyl-2,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate (720 g, 2.47 mmol) in dioxane (5 mL) is added 4N HCl in dioxane

Sources & evidence

ORD record
ord-3a5f409e7d7b482b8b75cede60d8a70e
Source dataset
uspto-grants-2010_09
Patent number
US07795262B2

Reaction notes

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