Benzyl Bromide → HCID 21738733, compound
Reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[C:5]#[N:6].[CH2:16](Br)[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[CH2:16]([O:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[C:10]1[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=1)[C:5]#[N:6])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1Participants
3
Procedure
The title compound was prepared in a similar manner to that described in Reference Example 20 using 3-hydroxy-4-phenylbenzonitrile instead of tert-butyl N-(3′-hydroxybiphenyl-4-ylmethyl)carbamate and benzyl bromide instead of 1-bromopropane.
Sources & evidence
- ORD record
- ord-0a51c1015e324d24b60baca17e8533e3
- Source dataset
- uspto-grants-2010_09
- Patent number
- US07795236B2
Reaction notes
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