2-Bromopyridine → 4-(2-Pyridyl)benzonitrile

HRID 1713288Notes

Reaction equation

HRID 1713288 reaction equation
Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][N:3]=1.[C:8]([C:10]1[CH:15]=[CH:14][C:13](B(O)O)=[CH:12][CH:11]=1)#[N:9]>>[N:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[C:13]1[CH:14]=[CH:15][C:10]([C:8]#[N:9])=[CH:11][CH:12]=1

Participants

3

Reactant 2

HCID 79732-BromopyridineHCID 27343264-Cyanophenylboronic acid

Product 1

HCID 15152384-(2-Pyridyl)benzonitrile

Procedure

The title compound was prepared in a similar manner to that described in Reference Example 11 using 2-bromopyridine instead of 1-bromo-3-pentyloxybenzene and 4-cyanophenylboronic acid instead of tert-butyl N-[ 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolane-2-yl)-benzyl]carbamate.

Sources & evidence

ORD record
ord-8d9f7570711e42dda2d720e302ff1e8a
Source dataset
uspto-grants-2010_09
Patent number
US07795236B2

Reaction notes

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