Piperidine → HCID 67542045, compound

HRID 1713306Notes

Reaction equation

HRID 1713306 reaction equation
Cl[CH2:2][CH2:3][CH2:4][O:5][C:6]1[CH:7]=[C:8]([C:12]2[CH:17]=[CH:16][C:15]([CH2:18][NH:19][C:20](=[O:26])[O:21][C:22]([CH3:25])([CH3:24])[CH3:23])=[CH:14][CH:13]=2)[CH:9]=[CH:10][CH:11]=1.[NH:27]1[CH2:32][CH2:31][CH2:30][CH2:29][CH2:28]1>>[N:27]1([CH2:2][CH2:3][CH2:4][O:5][C:6]2[CH:7]=[C:8]([C:12]3[CH:17]=[CH:16][C:15]([CH2:18][NH:19][C:20](=[O:26])[O:21][C:22]([CH3:25])([CH3:24])[CH3:23])=[CH:14][CH:13]=3)[CH:9]=[CH:10][CH:11]=2)[CH2:32][CH2:31][CH2:30][CH2:29][CH2:28]1

Participants

3

Reactant 2

HCID 8082PiperidineHCID 67455608HCID 67455608, compound

Product 1

HCID 67542045HCID 67542045, compound

Procedure

The title compound was prepared in a similar manner to that described in Reference Example 139 using tert-butyl N-[3′-(3-chloropropoxy)biphenyl-4-ylmethyl]carbamate instead of 3-(3-chloropropoxy)-4-phenylbenzonitrile and piperidine instead of pyrrolidine.

Sources & evidence

ORD record
ord-9fc155512efd4492a33a23a565232a7e
Source dataset
uspto-grants-2010_09
Patent number
US07795236B2

Reaction notes

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