Hydrochloric Acid → 6-Methoxy-3-(2-nitro-phenylsulfanyl)-1-pyridin-2-ylmethyl-1H-indole monohydrochloride

HRID 1713405Notes

Reaction equation

HRID 1713405 reaction equation
[CH3:1][O:2][C:3]1[CH:11]=[C:10]2[C:6]([C:7]([S:19][C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=3[N+:26]([O-:28])=[O:27])=[CH:8][N:9]2[CH2:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=2)=[CH:5][CH:4]=1.[ClH:29]>C(Cl)Cl>[ClH:29].[CH3:1][O:2][C:3]1[CH:11]=[C:10]2[C:6]([C:7]([S:19][C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=3[N+:26]([O-:28])=[O:27])=[CH:8][N:9]2[CH2:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=2)=[CH:5][CH:4]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 594638406-Methoxy-3-(2-nitro-phenylsulfanyl)-1-pyridin-2-ylmethyl-1H-indole

Product 1

HCID 667754566-Methoxy-3-(2-nitro-phenylsulfanyl)-1-pyridin-2-ylmethyl-1H-indole monohydrochloride

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To a solution of 6-Methoxy-3-(2-nitro-phenylsulfanyl)-1-pyridin-2-ylmethyl-1H-indole in methylene chloride was passed HCl-gas till the organic salt crystallised. The title compound was isolated by filtration.

Workup

  1. customcrystallised

Sources & evidence

ORD record
ord-755377d098e14b8ea31e9e632c5d472b
Source dataset
uspto-grants-2010_09
Patent number
US07795280B2

Reaction notes

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