HuagongsheHuagongshe Chemistry Print Report · For research reference only
Flt-3 Inhibitor III → N-[3-[(Dimethylamino)methyl]phenyl]-5-phenyl-2-thiazolamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Flt-3 Inhibitor III | HCID 11772958 | — |
| Reactant | (3-Dimethylaminomethyl-phenyl)-thiourea | HCID 18621787 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | N-[3-[(Dimethylamino)methyl]phenyl]-5-phenyl-2-thiazolamine | HCID 11243816 | — |
Reaction Steps
The title compound is prepared as described in Example 1 for (5-phenyl-thiazol-2-yl)-[4-(2-pyrrolidin-1-yl-ethoxy)phenyl]-amine but using (3-dimethylaminomethyl-phenyl)-thiourea. Title compound: ES-MS: 310.1 [M+H]+; single peak at tR=6.65 min (System 1); Rf=0.63 (CH2Cl2/MeOH, 80/20).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07795288B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-76a4dd3cd0244474a1b21a749cf3e666 |
| Source note | uspto-grants-2010_09 |