反应详情

The title compound is prepared as described in Example 1 for [4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-urea but using (3-isothiocyanato-benzyl)-dimethyl-amine. Title compound: ES-MS: 210.0 [M+H]+; single peak at tR=3.38 min (System 1); Rf=0.63 (CH2Cl2/MeOH, 80/20). (3-Isothiocyanato-benzyl)-dimethyl-amine is prepared as described in Example 1 for 1-[2-(4-isothiocyanato-phenoxy)ethyl]-pyrrolidine but using 3-dimethylaminomethyl-phenylamine. (3-Isothiocyanato-benzyl)dimethyl-amine is obtained and used as an impure crude material.

1. customThe title compound is prepared
2. custom(3-Isothiocyanato-benzyl)-dimethyl-amine is prepared