Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(4-Isothiocyanatophenyl)-4-methylpiperazine → [4-(4-Methylpiperazin-1-yl)phenyl]thiourea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(4-Isothiocyanatophenyl)-4-methylpiperazine | HCID 13718397 | — |
| 반응물 | [4-(2-Pyrrolidin-1-yl-ethoxy)-phenyl]-urea | HCID 68704441 | — |
| 용매 | Dichloromethane methanol | HCID 21226129 | — |
| 생성물 | [4-(4-Methylpiperazin-1-yl)phenyl]thiourea | HCID 39146979 | — |
반응 단계
The title compound is prepared as described in Example 1 for [4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-urea but using 1-(4-isothiocyanato-phenyl)-4-methyl-piperazine and stirring the reaction mixture at RT for 17 h. Title compound: ES-MS: 251.0 [M+H]+; major peak at tR=3.56 min (System 1); Rf=0.27 (CH2Cl2/MeOH, 80/20).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07795288B2 |
| 출처 데이터셋 | uspto-grants-2010_09 |
| ORD ID | ord-746305e35e8f487e818aa19cb3104da5 |
| 출처 메모 | uspto-grants-2010_09 |