HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(2-(Pyrrolidin-1-yl)ethoxy)aniline → 4-[2-(Dimethylamino)ethoxy]aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(2-(Pyrrolidin-1-yl)ethoxy)aniline | HCID 6493749 | — |
| Reactant | N,N-Dimethylaminoethyl chloride hydrochloride | HCID 11636816 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | 4-[2-(Dimethylamino)ethoxy]aniline | HCID 6484655 | — |
Reaction Steps
The title compound is prepared as described in Example 1 for 4-(2-pyrrolidin-1-yl-ethoxy)-phenylamine but using 1-chloro-2-dimethylaminoethane hydrochloride. Title compound: ES-MS: 181.2 [M+H]+; Rf=0.18 (CH2Cl2/MeOH, 70/30).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07795288B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-9114ea4742c84653a832183649c7710b |
| Source note | uspto-grants-2010_09 |