HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholine, 4-(2-chloroethyl)-, hydrochloride (1:1) → HCID 58923515, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholine, 4-(2-chloroethyl)-, hydrochloride (1:1) | HCID 77210 | — |
| Reactant | {5-[4-(3-Dimethylamino-propoxy)-phenyl]-thiazol-2-yl}phenyl-amine | HCID 11245147 | — |
| Reactant | 4-(5-Thiophen-3-yl-thiazol-2-yl-amino)-phenol | HCID 11288835 | — |
| Product | HCID 58923515 | HCID 58923515 | — |
Reaction Steps
The title compound is prepared as described in Example 8 for {5-[4-(3-dimethylamino-propoxy)-phenyl]-thiazol-2-yl}-phenyl-amine but starting from 4-(5-thiophen-3-yl-thiazol-2-yl-amino)-phenol (Example 12) and using (2-chloroethyl)-morpholine hydrochloride. MPLC (CH3CN/H2O/TFA) purification affords the title compound: ES-MS: 388.0 [M+H]+; single peak at tR=2.80 min (System 2).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07795288B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-8113d2ef660a4de7a4993e470fc3f862 |
| Source note | uspto-grants-2010_09 |