HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(5-Thiophen-3-yl-thiazol-2-yl-amino)-phenol → 4-[5-(2-Chloro-phenyl)-thiazol-2-ylamino]-phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(5-Thiophen-3-yl-thiazol-2-yl-amino)-phenol | HCID 11288835 | — |
| Reactant | 2-(2-Chlorophenyl)acetaldehyde | HCID 11378624 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | 4-[5-(2-Chloro-phenyl)-thiazol-2-ylamino]-phenol | HCID 58923528 | — |
Reaction Steps
The title compound is prepared as described in Example 12 (Procedure B) for 4-(5-thiophen-3-yl-thiazol-2-yl-amino)-phenol but starting from (2-chlorophenyl)-acetaldehyde. The title compound: ES-MS: 303.0 [M+H]+; single peak at tR=3.59 min (System 2); Rf=0.21 (CH2Cl2/MeOH, 95/5).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07795288B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-8984deac894746eba4a238f8916e6664 |
| Source note | uspto-grants-2010_09 |