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HRID1713670

反应详情

EQUATION

反应方程式

HRID 1713670 的结构方程式

REACTANTS

反应物

3
结构：c1ccc(-c2cnc(Nc3ccc(OCCN4CCCC4)cc3)s2)cc1
HCID11772958

未命名化合物

结构：CN1CCN(c2ccc(NC(N)=S)cc2)CC1
HCID39146979

未命名化合物

结构：O=CCc1cccc(-c2ccsc2)c1
HCID58923511

未命名化合物

PRODUCTS

生成物

1
结构：CN1CCN(c2ccc(Nc3ncc(-c4cccc(-c5ccsc5)c4)s3)cc2)CC1
HCID58923522

未命名化合物

PROCEDURE

实验过程

The title compound is prepared as described in Example 1 for (5-phenyl-thiazol-2-yl)-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amine but using (3-thiophen-3-yl-phenyl)-acetaldehyde and [4-(4-methyl-piperazin-1-yl)-phenyl]-thiourea (Example 5). MPLC (CH3CN/H2O/TFA) purification affords the title compound: ES-MS: 435.0 [M+3]+; single peak at tR=3.09 min (System 2); Rf=0.25 (CH2Cl2/MeOH, 90/10).

WORKUP

后处理

  1. customThe title compound is prepared
  2. customMPLC (CH3CN/H2O/TFA) purification