2-(Thiophen-3-yl)acetaldehyde → (3-Thiophen-3-yl-phenyl)-acetaldehyde

HRID 1713671Notes

Reaction equation

HRID 1713671 reaction equation
S1C=CC(CC=O)=C1.[S:9]1[CH:13]=[CH:12][C:11]([C:14]2[CH:15]=[C:16]([CH2:20][CH2:21][OH:22])[CH:17]=[CH:18][CH:19]=2)=[CH:10]1>C(Cl)Cl.CCOCC>[S:9]1[CH:13]=[CH:12][C:11]([C:14]2[CH:15]=[C:16]([CH2:20][CH:21]=[O:22])[CH:17]=[CH:18][CH:19]=2)=[CH:10]1

Participants

4

Reactant 2

HCID 141408302-(Thiophen-3-yl)acetaldehydeHCID 199171332-(3-Thiophen-3-yl-phenyl)-ethanol

Product 1

HCID 58923511(3-Thiophen-3-yl-phenyl)-acetaldehyde

Reagents, catalysts & solvents 1

HCID 21881112Ethyl ether methylene chlorideSolvent

Procedure

The title compound is prepared as described in Example 12 (Procedure B) for 3-thiophenylacetaldehyde but using 2-(3-thiophen-3-yl-phenyl)-ethanol. The title compound: ES-MS: 200.9 [M−H]−; single peak at tR=4.53 min (System 2); Rf=0.63 (CH2Cl2/Et2O, 95/5).

Workup

  1. customThe title compound is prepared

Sources & evidence

ORD record
ord-ba154b68de2c44cb8bb2ffc9ab34776c
Source dataset
uspto-grants-2010_09
Patent number
US07795288B2

Reaction notes

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