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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1713674Generated: November 1, 2026

4-(5-Thiophen-3-yl-thiazol-2-yl-amino)-phenol → 4-[5-(3-Thiophen-3-yl-phenyl)-thiazol-2-ylamino]-phenol

https://huagongshe.com/reaction/1713674

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(5-Thiophen-3-yl-thiazol-2-yl-amino)-phenolHCID 11288835—
Reactant(3-Thiophen-3-yl-phenyl)-acetaldehydeHCID 58923511—
Product4-[5-(3-Thiophen-3-yl-phenyl)-thiazol-2-ylamino]-phenolHCID 58923506—

Reaction Steps

The title compound is prepared as described in Example 12 (Procedure B) for 4-(5-thiophen-3-yl-thiazol-2-yl-amino)-phenol but starting from (3-thiophen-3-yl-phenyl)-acetaldehyde (Example 25). The title compound: ES-MS: 350.9 [M+H]+; single peak at tR=4.16 min (System 2).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07795288B2
Source datasetuspto-grants-2010_09
ORD IDord-a965e684f7b345d3a24bc071a3a601bd
Source noteuspto-grants-2010_09