反应详情

The title compound is prepared as described in Example 7 for 4-{2-[4-(2-pyrrolidin-1-yl-ethoxy)-phenylamino]-thiazol-5-yl}-phenol but starting from (4-methoxy-2-methyl-phenyl)-(5-thiophen-3-yl-thiazol-2-yl)-amine and using 4 equivalents of BBr3. Title compound: ES-MS: 289.0 [M+H]+; single peak at tR=3.33 min (System 2); Rf=0.15 (CH2Cl2/MeOH, 95/5).

1. customThe title compound is prepared