HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(5-Thiophen-3-yl-thiazol-2-yl-amino)-phenol → (4-Methoxy-2-methyl-phenyl)-(5-thiophen-3-yl-thiazol-2-yl)-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(5-Thiophen-3-yl-thiazol-2-yl-amino)-phenol | HCID 11288835 | — |
| Reactant | (4-Methoxy-2-methylphenyl)thiourea | HCID 20481024 | — |
| Reactant | (3-Thiophen-3-yl-phenyl)-acetaldehyde | HCID 58923511 | — |
| Product | (4-Methoxy-2-methyl-phenyl)-(5-thiophen-3-yl-thiazol-2-yl)-amine | HCID 58923520 | — |
Reaction Steps
The title compound is prepared as described in Example 12 (Procedure B) for 4-(5-thiophen-3-yl-thiazol-2-yl-amino)-phenol but starting from (3-thiophen-3-yl-phenyl)-acetaldehyde (Example 25) and (4-methoxy-2-methyl-phenyl)-thiourea. The title compound: ES-MS: 303.0 [M+H]+; single peak at tR=3.96 min (System 2).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07795288B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-afe45da642f5427bb2cd2e32875a51fa |
| Source note | uspto-grants-2010_09 |