反应详情

The title compound is prepared as described in Example 7 for 4-{2-[4-(2-pyrrolidin-1-yl-ethoxy)-phenylamino]-thiazol-5-yl}-phenol but starting from (4-methoxy-2-trifluoromethyl-phenyl)-(5-thiophen-3-yl-thiazol-2-yl)-amine and using 4 equivalents of BBr3. Title compound: ES-MS: 342.9 [M+H]+; single peak at tR=3.71 min (System 2); Rf=0.47 (CH2Cl2/MeOH, 90/10).

1. customThe title compound is prepared