Urea → (4-Methoxy-2-methylphenyl)thiourea

HRID 1713682Notes

Reaction equation

HRID 1713682 reaction equation
[NH2:1]C(N)=O.[N:5]([C:8]1[CH:13]=[CH:12][C:11]([O:14][CH3:15])=[CH:10][C:9]=1[C:16](F)(F)F)=[C:6]=[S:7]>>[CH3:15][O:14][C:11]1[CH:12]=[CH:13][C:8]([NH:5][C:6]([NH2:1])=[S:7])=[C:9]([CH3:16])[CH:10]=1

Participants

3

Reactant 2

HCID 1176UreaHCID 589235271-Isothiocyanato-4-methoxy-2-trifluoromethyl-benzene

Product 1

HCID 20481024(4-Methoxy-2-methylphenyl)thiourea

Procedure

The title compound is prepared as described in Example 1 for [4-2-pyrrolidin-1-yl-ethoxy)-phenyl]-urea but using 1-isothiocyanato-4-methoxy-2-trifluoromethyl-benzene. Title compound: ES-MS: 251.0 [M+H]+; single peak at tR=3.13 min (System 2).

Workup

  1. customThe title compound is prepared

Sources & evidence

ORD record
ord-67224fc48daa4ae9b80eb60c3e27ae39
Source dataset
uspto-grants-2010_09
Patent number
US07795288B2

Reaction notes

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