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HRID1713688

反应详情

EQUATION

反应方程式

HRID 1713688 的结构方程式

REACTANTS

反应物

3
结构：CC(C)N(CCCl)C(C)C.Cl
HCID77942

N-(2-chloroethyl)-N-(propan-2-yl)propan-2-amine hydrochloride

C8H19Cl2N

结构：CN(C)CCCOc1ccc(-c2cnc(Nc3ccccc3)s2)cc1
HCID11245147

未命名化合物

结构：Oc1ccc(Nc2ncc(-c3ccsc3)s2)c(C(F)(F)F)c1
HCID58923523

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)N(CCOc1ccc(Nc2ncc(-c3ccsc3)s2)c(C(F)(F)F)c1)C(C)C
HCID58923535

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CO.ClCCl
溶剂HCID21226129

未命名化合物

PROCEDURE

实验过程

The title compound is prepared as described in Example 8 for {5-[4-(3-dimethylamino-propoxy)-phenyl]-thiazol-2-yl}phenyl-amine but starting from 4-(5-thiophen-3-yl-thiazol-2-ylamino)-3-trifluoromethyl-phenol (Example 28) and using (2-chloroethyl)-diisopropylamine hydrochloride. The title compound: ES-MS: 469.9 [M+H]+; single peak at tR=3.67 min (System 2); Rf=0.38 (CH2Cl2/MeOH, 90/10).

WORKUP

后处理

  1. customThe title compound is prepared