[4-(4-Acetylpiperazin-1-yl)-3-methylphenyl]amine → 4-(4-Acetyl-1,4-diazepan-1-yl)aniline

Participants

Reaction Steps

Following the general procedure of Intermediate 36 but using 1-acetyl-4-(4-nitrophenyl)-1,4-diazepane (Intermediate 70) as starting material there was thus obtained the title compound in 97% yield; 1H NMR δ: 6.55-6.46 (4H, m), 4.30 (2H, br s), 3.59-3.48 (3H, m), 3.41-3.26 (5H, m), 1.99-1.72 (5H, m); MS m/e MH+: 234.

Provenance & Evidence