Hydrochloric Acid → HCID 59464293, compound

Participants

Reaction Steps

4M HCl in 1,4-dioxane (70 mL) was added to tert-butyl 3-[(5-{[(6-morpholin-4-ylpyridin-3-yl)amino]carbonyl}-1,3,4-oxadiazol-2-yl)amino]benzoate (3.22 g, 6.90 mmol) and the suspension stirred for 18 hours. All volatiles were removed in vacuo and the residue triturated with Et2O (20 mL), the solid filtered, washed with Et2O (2×10 mL), hexane (2×10 mL) to give the title compound (2.80 g, 99%) as a cream powder; MS m/e (MH)+ 411

Provenance & Evidence