HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 1-but-3-en-1-yl-3-cyclohexyl-2-(2-vinylphenyl)-1H-indole-6-carboxylate → HCID 68505449, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 1-but-3-en-1-yl-3-cyclohexyl-2-(2-vinylphenyl)-1H-indole-6-carboxylate | HCID 44155798 | — |
| Catalyst | HCID 42640442 | HCID 42640442 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 68505449 | HCID 68505449 | 68% |
Reaction Steps
Methyl 1-but-3-en-1-yl-3-cyclohexyl-2-(2-vinylphenyl)-1H-indole-6-carboxylate was dissolved in DCM (0.02M) and treated with Zhan catalyst 1 (0.3 eq) at 35° C. for 1 h. After evaporation of solvent in vacuo the residue was purified by chromatography (PE/EtOAc 9:1) to afford the title compound (68%); MS (ES+) m/z 386 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07795247B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-1023c48b2e564c5a95454ef47d3dfae8 |
| Source note | uspto-grants-2010_09 |