Trifluoroacetic acid → HCID 68510603, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of methyl 6-(2-tert-butoxy-2-oxoethyl)-14-cyclohexyl-5,6,7,8-tetrahydroindolo[2,1-a][2,5]benzodiazocine-11-carboxylate in a 1:1 mixture DCM/H2O (0.05 M) was added a large excess (>100 eq) of TFA and the solution heated for 4 h at 45° C. The volatiles were then removed in vacuo and the crude product was used in the next step without further purification; MS (ES+) m/z 447 (M+H)+.

Provenance & Evidence