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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1714397Generated: October 31, 2026

Cyclobutanecarboxylic acid → HCID 178523670, compound

https://huagongshe.com/reaction/1714397

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclobutanecarboxylic acidHCID 19494—
ReactantHCID 178511520HCID 178511520—
ProductHCID 178523670HCID 178523670—

Reaction Steps

According to the synthesis of example 1 the title compound was prepared from Trans(4-{2-[4-(2,6-dichloro-4-fluoro-phenoxy)-piperidin-1-yl]-ethyl}-cyclohexyl)-amine and cyclobutanecarboxylic acid. Preparative HPLC on reversed phase eluting with acetonitrile/water yielded the title compound. MS (m/e): 471.0 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07795437B2
Source datasetuspto-grants-2010_09
ORD IDord-d371a5b5f7364227bfd418b2f548320c
Source noteuspto-grants-2010_09