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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1714399Generated: November 2, 2026

Oxane-4-carboxylic acid → HCID 178523669, compound

https://huagongshe.com/reaction/1714399

Reaction equation

Participants

RoleNameHCIDCharge
ReactantOxane-4-carboxylic acidHCID 219302—
ReactantHCID 178511519HCID 178511519—
ProductHCID 178523669HCID 178523669—

Reaction Steps

According to the synthesis of example 19 the title compound was prepared from Trans(4-{2-[4-(2,4,5-trifluoro-phenoxy)-piperidin-1-yl]-ethyl}-cyclohexyl)-amine and tetrahydro-pyran-4-carboxylic acid. Preparative HPLC on reversed phase eluting with acetonitrile/water yielded the title compound. MS (m/e): 469.5 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07795437B2
Source datasetuspto-grants-2010_09
ORD IDord-cf8fba6d3c1a4d049bdb917fd9bab0e1
Source noteuspto-grants-2010_09