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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1714402Generated: October 31, 2026

2-Chloro-6-fluorobenzonitrile → HCID 68499903, compound

https://huagongshe.com/reaction/1714402

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-6-fluorobenzonitrileHCID 69587—
ReactantTert-butyl 4-hydroxypiperidine-1-carboxylateHCID 643502—
ProductHCID 68499903HCID 68499903—

Reaction Steps

2-Chloro-6-(piperidin-4-yloxy)-benzonitrile hydrochloride was prepared in a manner analogous to that described in example 59.2 from 2-chloro-6-fluoro-benzonitrile and 4-hydroxy-piperidine-1-carboxylic acid tert-butyl ester. White solid. MS (m/z): 237.0 ([M+H]+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07795437B2
Source datasetuspto-grants-2010_09
ORD IDord-0caaa75c2a8445a898e3ebe25acda033
Source noteuspto-grants-2010_09