Benzylamine → HCID 178502581, compound

HRID 1714490Notes

Reaction equation

HRID 1714490 reaction equation
[CH3:1][O:2][CH2:3][PH:4]([CH2:6][CH2:7][CH:8]=O)=[O:5].[CH2:10]([NH2:17])[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>C1(C)C=CC=CC=1>[CH2:10]([N:17]=[CH:8][CH2:7][CH2:6][PH:4]([CH2:3][O:2][CH3:1])=[O:5])[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Participants

4

Reactant 2

HCID 7504BenzylamineHCID 178502582HCID 178502582, compound

Product 1

HCID 178502581HCID 178502581, compoundYield 91%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Sodium sulfate anhydride (120 mg) was added to a solution obtained by dissolving 3-(methoxymethylphosphinyl)-propanal (60 mg) and benzylamine (42.8 mg) in toluene (3 ml), then the resultant solution was stirred for an hour at room temperature. Sodium sulfate was filtered out, and the resultant filtrate was concentrated to obtain N-benzyl-3-(methoxymethylphosphinyl)-propylideneamine (87 mg).

Workup

  1. customobtained
  2. filtrationSodium sulfate was filtered out
  3. concentrationthe resultant filtrate was concentrated

Sources & evidence

ORD record
ord-d7b5dd0b063949499b86205db004b0b4
Source dataset
uspto-grants-2010_09
Patent number
US07795464B2

Reaction notes

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