Formaldehyde → HCID 59235866, compound

HRID 1714693Notes

Reaction equation

HRID 1714693 reaction equation
[NH:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1.[CH2:6]=O.[CH3:8][O:9][C:10]1[CH:15]=[C:14]([CH:16]=[O:17])[CH:13]=[CH:12][C:11]=1[OH:18]>C(O)C>[OH:18][C:11]1[C:12]([CH2:6][N:1]2[CH2:5][CH2:4][CH2:3][CH2:2]2)=[CH:13][C:14]([CH:16]=[O:17])=[CH:15][C:10]=1[O:9][CH3:8]

Participants

5

Reactant 3

HCID 712FormaldehydeHCID 1183VanillinHCID 31268Pyrrolidine

Product 1

HCID 59235866HCID 59235866, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

21.3 g (0.30 mol) of pyrrolidine were added to 24.0 g (0.30 mol) of a 37% aqueous formaldehyde solution in 180 ml of ethanol. Then 30.4 g (0.20 mol) of 4-hydroxy-3-methoxybenzaldehyde (vanillin) were added. The mixture was refluxed for three hours. A solid began to precipitate out as early as during cooling, which was filtered out after complete cooling of the reaction batch and dried.

Workup

  1. temperatureThe mixture was refluxed for three hours
  2. customto precipitate out as early as
  3. temperatureduring cooling
  4. filtrationwhich was filtered out
  5. temperatureafter complete cooling of the reaction batch
  6. customdried

Sources & evidence

ORD record
ord-8afe80b785524da1a0868874df60c4be
Source dataset
uspto-grants-2010_09
Patent number
US07799096B2

Reaction notes

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