Formaldehyde → HCID 13280357, compound

HRID 1714694Notes

Reaction equation

HRID 1714694 reaction equation
[NH:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH2:7]=O.[CH3:9][O:10][C:11]1[CH:16]=[C:15]([CH:17]=[O:18])[CH:14]=[CH:13][C:12]=1[OH:19]>C(O)C>[OH:19][C:12]1[C:13]([CH2:7][N:1]2[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]2)=[CH:14][C:15]([CH:17]=[O:18])=[CH:16][C:11]=1[O:10][CH3:9]

Participants

5

Reactant 3

HCID 712FormaldehydeHCID 1183VanillinHCID 8082Piperidine

Product 1

HCID 13280357HCID 13280357, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

25.5 g (0.30 mol) of piperidine were added to 24.0 g (0.30 mol) of a 37% aqueous formaldehyde solution in 180 ml of ethanol. Then 30.4 g (0.20 mol) of 4-hydroxy-3-methoxybenzaldehyde (vanillin) were added. The reaction mixture was refluxed for one hour. A solid began to precipitate out as early as during cooling, which was filtered out after complete cooling of the reaction batch and dried.

Workup

  1. temperatureThe reaction mixture was refluxed for one hour
  2. customto precipitate out as early as
  3. temperatureduring cooling
  4. filtrationwhich was filtered out
  5. temperatureafter complete cooling of the reaction batch
  6. customdried

Sources & evidence

ORD record
ord-449f025dc7584ee38f2e7051b5216b62
Source dataset
uspto-grants-2010_09
Patent number
US07799096B2

Reaction notes

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