反应详情

To 7N-ammonia-methanol solution, 170 g of ethyl 2-oxocyclohexanecarboxylate was added and stirred for an overnight at room temperature. Concentrating the solvent under reduced pressure, crude crystals were obtained, which were recrystallized from ethyl acetate-n-hexane to provide 152 g (90%) of 2-aminocyclohex-1-enecarboxylic acid ethyl ester.

1. concentrationConcentrating the solvent under reduced pressure
2. customcrude crystals were obtained
3. customwhich were recrystallized from ethyl acetate-n-hexane