HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 2-oxocyclohexanecarboxylate → Ethyl 2-aminocyclohex-1-ene-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 2-oxocyclohexanecarboxylate | HCID 95543 | — |
| Reactant | Ammonia methanol | HCID 21705897 | — |
| Product | Ethyl 2-aminocyclohex-1-ene-1-carboxylate | HCID 312929 | 90% |
Reaction Steps
To 7N-ammonia-methanol solution, 170 g of ethyl 2-oxocyclohexanecarboxylate was added and stirred for an overnight at room temperature. Concentrating the solvent under reduced pressure, crude crystals were obtained, which were recrystallized from ethyl acetate-n-hexane to provide 152 g (90%) of 2-aminocyclohex-1-enecarboxylic acid ethyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07799775B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-48f2d7fec8124db9b498d02640f7a57e |
| Source note | uspto-grants-2010_09 |