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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1714885Generated: November 3, 2026

HCID 57647141, compound → HCID 68508869, compound

https://huagongshe.com/reaction/1714885

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 57647141HCID 57647141—
CatalystPalladiumHCID 23938—
SolventEthyl AcetateHCID 8857—
ProductHCID 68508869HCID 68508869—

Reaction Steps

A mixture of 5-nitro-2-{4-[2-(trifluoromethyl)phenoxy]piperidin-1-yl}pyridine (1.6 g, 4.4 mmol) and 10% Pd/C (300 mg) in EtOAc (100 mL) was hydrogenated at 50 psi overnight. The catalyst was filtered off through celite. The filtrate was removed in vacuo to give the title compound as a light brown gum.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07799787B2
Source datasetuspto-grants-2010_09
ORD IDord-9cd6f92483534096959bdf2675483c9c
Source noteuspto-grants-2010_09