HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 57647141, compound → HCID 68508869, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 57647141 | HCID 57647141 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 68508869 | HCID 68508869 | — |
Reaction Steps
A mixture of 5-nitro-2-{4-[2-(trifluoromethyl)phenoxy]piperidin-1-yl}pyridine (1.6 g, 4.4 mmol) and 10% Pd/C (300 mg) in EtOAc (100 mL) was hydrogenated at 50 psi overnight. The catalyst was filtered off through celite. The filtrate was removed in vacuo to give the title compound as a light brown gum.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07799787B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-9cd6f92483534096959bdf2675483c9c |
| Source note | uspto-grants-2010_09 |