反应详情

A mixture of Example 277D (3.1 g, 9.7 mmol), concentrated NH4OH (62 mL), and dioxane (62 mL) was heated to 150° C. in a sealed tube for 36 hours, filtered, and concentrated to provide a soid which was triturated with water (20 mL), collected and dried to give 2.1 g (84% yield) of the desired product. MS (ESI(+)) m/e 258.9, 260.8 (M+H)+.

1. filtrationfiltered
2. concentrationconcentrated
3. customto provide a soid which
4. customwas triturated with water (20 mL)
5. customcollected
6. customdried