Ethanol → N-(5-tert-butyl-2-methylphenyl)-2-chloro-5-fluoropyrimidin-4-amine
Reaction equation
[CH3:10][c:11]1[c:12]([NH2:13])[cH:14][c:15]([C:18]([CH3:19])([CH3:20])[CH3:21])[cH:16][cH:17]1.[CH3:31][CH2:32][OH:33].[CH:22]([N:23]([CH:24]([CH3:25])[CH3:26])[CH2:27][CH3:28])([CH3:29])[CH3:30].[Cl:1][c:2]1[n:3][cH:4][c:5]([F:9])[c:6]([Cl:8])[n:7]1>>[Cl:1][c:2]1[n:3][cH:4][c:5]([F:9])[c:6]([NH:13][c:12]2[c:11]([CH3:10])[cH:17][cH:16][c:15]([C:18]([CH3:19])([CH3:20])[CH3:21])[cH:14]2)[n:7]1Participants
5
Sources & evidence
- ORD record
- ord-47e31ba5481547fd9ec90b4ccb86fd2a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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