HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → N-(6-benzenesulfonyl-naphthalen-1-ylmethyl)-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | C-(6-Benzenesulfonyl-naphthalen-1-yl)-methylamine | HCID 59028770 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | N-(6-benzenesulfonyl-naphthalen-1-ylmethyl)-acetamide | HCID 59028777 | — |
Reaction Steps
C-(6-Benzenesulfonyl-naphthalen-1-yl)-methylamine is dissolved in pyridine and acetyl chloride is added. The reaction mixture is stirred at room temperature and then quenched by addition of water. The mixture is extracted with EtOAc, and the organic layer is dried (MgSO4), filtered, and concentrated under reduced pressure to give N-(6-benzenesulfonyl-naphthalen-1-ylmethyl)-acetamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07799797B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-c3f39a7750534187aa98626e16d76b50 |
| Source note | uspto-grants-2010_09 |