Hydrochloric Acid → HCID 68509200, compound

Participants

Reaction Steps

To a solution of 1-(1-acetyl-piperidin-4-yl)-1,5-dihydro-imidazo[4,5-c]pyridin-4-one (6.00 g, 23.05 mmol) in ethanol (48 mL) was added conc. HCl (24 mL) and the reaction mixture heated to reflux for 16 h. The solvent was removed under reduced pressure and the crude product used in the consecutive step without further purification assuming quantitative deprotection and formation of the dihydrochloride salt. MS (ISP): 219.2 [M+H]+.

Provenance & Evidence