HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 43219016, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 4-(Chlorosulfonyl)benzoic acid | HCID 82385 | — |
| Reactant | Methyl beta-alanate | HCID 192794 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 43219016 | HCID 43219016 | — |
Reaction Steps
It is obtained by reacting 4-chlorosulfonyl-benzoic acid (1 eq) with H-βAla-OMe×HCl in CH2Cl2 using diisopropylethylamine (2 eq) as base. After 30 minutes at room temperature the reaction mixture is extracted with water and the organic layer is dried over Na2SO4. Removal of the solvent gives the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07799812B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-0ac2cd5667ec4cfbb11e2ca7df37bb19 |
| Source note | uspto-grants-2010_09 |