化工社化工社 化学情報印刷レポート · 研究参考用
Cesium carbonate → 2-([6-(Methylsulfonyl)pyridin-3-yl]oxy)-5-nitrobenzaldehyde
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Cesium carbonate | HCID 10796 | — |
| 反応物 | N-methyl-2-pyrrolidone | HCID 13387 | — |
| 反応物 | 2-Chloro-5-nitrobenzaldehyde | HCID 72933 | — |
| 反応物 | 6-(Methylsulfonyl)pyridin-3-ol | HCID 23145196 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 2-([6-(Methylsulfonyl)pyridin-3-yl]oxy)-5-nitrobenzaldehyde | HCID 86630116 | — |
反応手順
Cesium carbonate (10 g) was added to an N-methylpyrrolidinone (70 ml) solution of 2-chloro-5-nitrobenzaldehyde (5.0 g) and 6-(methylsulfonyl)-3-pyridinol (5 g) obtained in Reference Example 2, and stirred at room temperature for 3 hours. Water was added, then the formed crystal was collected by filtration to obtain the entitled compound as a pale brown solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07799820B2 |
| 出典データセット | uspto-grants-2010_09 |
| ORD ID | ord-a5d02a002bdb411eb8d2fa507a969e05 |
| 出典メモ | uspto-grants-2010_09 |