HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexene → 2-Amino-5-(4-morpholinyl)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexene | HCID 8079 | — |
| Reactant | 5-(Morpholin-4-yl)-2-nitrobenzoic acid | HCID 7064080 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Amino-5-(4-morpholinyl)benzoic acid | HCID 7063887 | 90.8% |
Reaction Steps
The mixture of 6 g of 2-nitro-5-(morpholin-4-yl)benzoic acid, 15 mL of cyclohexene and 3 g of Pd/C (10%) is heated under reflux conditions in 120 mL of ethanol for 6 hours. The hot reaction mixture is filtered through celite filter. The filtrate is evaporated to obtain 4.8 g of the title compound. m.p.: 242° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07799922B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-b0bdb17d51b94f2496715e455fe4b28f |
| Source note | uspto-grants-2010_09 |