Phenol → HCID 57864775, compound

HRID 1715873Notes

Reaction equation

HRID 1715873 reaction equation
[I:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([C:17]2[CH:22]=[CH:21][C:20]([I:23])=[CH:19][CH:18]=2)([C:10]2[CH:15]=[CH:14][C:13]([I:16])=[CH:12][CH:11]=2)O)=[CH:4][CH:3]=1.[C:24]1([OH:30])[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1.S(=O)(=O)(O)O.[OH-].[Na+]>>[OH:30][C:24]1[CH:29]=[CH:28][C:27]([C:8]([C:17]2[CH:22]=[CH:21][C:20]([I:23])=[CH:19][CH:18]=2)([C:10]2[CH:15]=[CH:14][C:13]([I:16])=[CH:12][CH:11]=2)[C:5]2[CH:6]=[CH:7][C:2]([I:1])=[CH:3][CH:4]=2)=[CH:26][CH:25]=1

Participants

5

Reactant 4

HCID 996PhenolHCID 1118Sulfuric AcidHCID 14798Sodium HydroxideHCID 57864781HCID 57864781, compound

Product 1

HCID 57864775HCID 57864775, compoundYield 76%

Conditions

Temperature
80 °C

Procedure

10 parts by weight of tris(4-iodophenyl)methanol, 4.4 parts by weight of phenol, and 2 parts by weight of conc. sulfuric acid were put into a reaction vessel and stirred for 4 hours while heating at 80° C. After cooling, a 10% sodium hydroxide solution was added to the reaction solution, and stirring was carried out for 2 hours. A deposited precipitate was collected by filtration, thus giving 8.5 parts by weight of 4-hydroxyphenyl[tris(4-iodophenyl)]methane (yield: 76%).

Workup

  1. temperatureAfter cooling
  2. stirringstirring
  3. waitwas carried out for 2 hours
  4. filtrationA deposited precipitate was collected by filtration

Sources & evidence

ORD record
ord-df3027df42944689b80e8a0e38a554d6
Source dataset
uspto-grants-2010_09
Patent number
US07799949B2

Reaction notes

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