HCID 178526344, compound → 4-Pyridinecarbaldehyde oxime

HRID 1716174Notes

Reaction equation

HRID 1716174 reaction equation
O[C:2]1[CH:7]=[C:6]([CH:8]=[N:9][OH:10])[CH:5]=[CH:4][N:3]=1>C(O)(C)C>[N:3]1[CH:4]=[CH:5][C:6]([CH:8]=[N:9][OH:10])=[CH:7][CH:2]=1

Participants

3

Reactant 1

HCID 178526344HCID 178526344, compound

Product 1

HCID 127644-Pyridinecarbaldehyde oxime

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

One hundred mL of isopropanol was added to the resulting broth containing 0.27 g of 2-hydroxy-4-pyridinaldoxime obtained from the reaction with 4-pyridinaldoxime as a substance. After shaking for 30 minutes, the solid contents were removed by filtration. After an addition of 100 mL of water to the filtrate, the whole was concentrated under a reduced pressure, whereby isopropanol was removed to precipitate the crystals. The precipitated crystals were separated by filtration to obtain 0.20 g of crude crystals. The resulting crystals were washed by water, and then were separated by filtration to obtain 0.15 g of white crystals of 2-hydroxy-4-pyridinaldoxime (rate of isolated yield=53%). The structure of the crystals was identified by IR analysis, proton NMR analysis and MS analysis.

Sources & evidence

ORD record
ord-e53345d7cd0c49a3832c77f9b3efcc0f
Source dataset
uspto-grants-2010_09
Patent number
US07803585B2

Reaction notes

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