HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 66991494, compound → HCID 66991807, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 66991494 | HCID 66991494 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | HCID 66991807 | HCID 66991807 | 138% |
Reaction Steps
3-[3-Fluoro-4-(3-oxo-3-pyridin-3-yl-propenyl)-phenyl]-acrylic acid tert-butyl ester (550 mg, 1.55 mmol) was dissolved in DCM (15 ml) and TFA (5 ml). The resulting solution was stirred at RT for 4 h then the solvent was removed under vacuo giving 636 mg of 3-[3-fluoro-4-(3-oxo-3-pyridin-3-yl-propenyl)-phenyl]-acrylic acid as trifluoro acetate salt.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07803800B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-c435324a5c0944bea43e936b6d0516b2 |
| Source note | uspto-grants-2010_09 |