Trifluoroacetic acid → HCID 19049649, compound

Participants

Reaction Steps

A solution of {5-[4-(5-tert-butoxycarbonylamino-pentyl)-piperazin-1-yl]-pentyl}-carbamic acid tert-butyl ester (329 mg, 0.72 mmol) in DCM (10 mL) is treated with trifluoracetic acid (1 mL). The reaction was left to stir at RT for 4 days and then the solvent is removed in vacuo. The material was used crude and conversion was assumed quantitative to produce 5-[4-(5-amino pentyl)-piperazin-1-yl]-pentylamine.

Provenance & Evidence