反应详情

A solution of 3-benzyloxy-1-(toluene-4-sulfonylmethyl)-1H-pyridin-2-one (50 mg) from Step B in MeSO3H (1.5 mL) was stirred at room temperature for 20 min and then quenched with ice water. The solid was filtered off and washed with water. The crude product was re-dissolved in hot MeOH (1 mL) and removed un-dissolved brownish solid. The filtrate was concentrated in vacuo to give the titled compound. MS (EI) 280 (M+H)+.

1. customquenched with ice water
2. filtrationThe solid was filtered off
3. washwashed with water
4. dissolutionThe crude product was re-dissolved in hot MeOH (1 mL)
5. customremoved
6. dissolutionun-dissolved brownish solid
7. concentrationThe filtrate was concentrated in vacuo