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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1716343Generated: November 2, 2026

Chloroacetone → 1-methoxy-2-methylindolizine

https://huagongshe.com/reaction/1716343

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChloroacetoneHCID 6571—
Reactant2-(Methoxymethyl)pyridineHCID 253220—
Product1-methoxy-2-methylindolizineHCID 11321123—

Reaction Steps

This compound is obtained starting with 2-(methoxymethyl)pyridine and chloroacetone, using the Tschitschibabin reaction. The product is isolated in the form of a yellow oil which crystallizes in the freezer.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07803811B2
Source datasetuspto-grants-2010_09
ORD IDord-b0390b091ea34b17a5723e6f76c4929f
Source noteuspto-grants-2010_09