Hydrochloric Acid → 2-Methyl-5-(2-piperazin-1-ylethoxy)quinoline

HRID 171652Notes

Reaction equation

HRID 171652 reaction equation
[CH3:1][c:2]1[n:3][c:4]2[cH:5][cH:6][cH:7][c:8]([O:12][CH2:13][CH2:14][N:15]3[CH2:16][CH2:17][N:18]([C:21]([O:22][C:23]([CH3:24])([CH3:25])[CH3:26])=[O:27])[CH2:19][CH2:20]3)[c:9]2[cH:10][cH:11]1.[CH3:29][CH2:30][O:31][CH2:32][CH3:33].[CH3:34][CH2:35][OH:36].[ClH:28]>>[CH3:1][c:2]1[n:3][c:4]2[cH:5][cH:6][cH:7][c:8]([O:12][CH2:13][CH2:14][N:15]3[CH2:16][CH2:17][NH:18][CH2:19][CH2:20]3)[c:9]2[cH:10][cH:11]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 702EthanolHCID 3283Diethyl EtherHCID 11394642tert-Butyl 4-[2-(2-methylquinolin-5-yloxy)ethyl]piperazine-1-carboxylate

Product 1

HCID 112542672-Methyl-5-(2-piperazin-1-ylethoxy)quinoline

Sources & evidence

ORD record
ord-63fc6cabe2944827bb21342293c17b5a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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