HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Dioxane hydrochloride → HCID 68512392, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Dioxane hydrochloride | HCID 20443148 | — |
| Reactant | HCID 68513326 | HCID 68513326 | — |
| Product | HCID 68512392 | HCID 68512392 | — |
Reaction Steps
A solution of 4-(2-cyclopropyl-5-methyl-benzoimidazol-1-yl)-3-methoxy-piperidine-1-carboxylic acid tert-butyl ester (650 mg, 1.69 mmol) in a 4 M HCl/dioxane (3 mL) solution was stirred for 0.5 h. The solvent was removed to provide 2-cyclopropyl-1-(3-methoxy-piperidin-4-yl)-5-methyl-1H-benzoimidazole hydrochloride salt in quantitative yield without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07803816B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-76fbb124e5024dbebacf5ffa01b5abcf |
| Source note | uspto-grants-2010_09 |