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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1716566Generated: November 3, 2026

1,4-Dioxane hydrochloride → HCID 68512392, compound

https://huagongshe.com/reaction/1716566

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-Dioxane hydrochlorideHCID 20443148—
ReactantHCID 68513326HCID 68513326—
ProductHCID 68512392HCID 68512392—

Reaction Steps

A solution of 4-(2-cyclopropyl-5-methyl-benzoimidazol-1-yl)-3-methoxy-piperidine-1-carboxylic acid tert-butyl ester (650 mg, 1.69 mmol) in a 4 M HCl/dioxane (3 mL) solution was stirred for 0.5 h. The solvent was removed to provide 2-cyclopropyl-1-(3-methoxy-piperidin-4-yl)-5-methyl-1H-benzoimidazole hydrochloride salt in quantitative yield without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07803816B2
Source datasetuspto-grants-2010_09
ORD IDord-76fbb124e5024dbebacf5ffa01b5abcf
Source noteuspto-grants-2010_09