HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(3-Cyano-1H-Indol-5-yl)-3-phenyl-propionic acid ethyl ester → 5-(3-Hydroxy-1-phenyl-propyl)-1H-indole-3-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(3-Cyano-1H-Indol-5-yl)-3-phenyl-propionic acid ethyl ester | HCID 67355873 | — |
| Reactant | 4-(3-hydroxy-1-phenyl-propyl)-1H-indole-3-carbonitrile | HCID 67376264 | — |
| Product | 5-(3-Hydroxy-1-phenyl-propyl)-1H-indole-3-carbonitrile | HCID 67376759 | — |
Reaction Steps
5-(3-Hydroxy-1-phenyl-propyl)-1H-indole-3-carbonitrile LXV (1.24 g, 79%) was prepared from 3-(3-cyano-1H-Indol-5-yl)-3-phenyl-propionic acid ethyl ester using the procedure described for 4-(3-hydroxy-1-phenyl-propyl)-1H-indole-3-carbonitrile LX (see Example 14).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07803830B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-1d7e4738977c4704b46fae4f55acb668 |
| Source note | uspto-grants-2010_09 |